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Prevention and Management of Wasting and Nutritional Edema (Acute Malnutrition) in Infants and Children Under 5 Years

"last update: 28 April 2024"  

- Implementation considerations

To improve nutritional care and patient outcome, evidence-based recommendations must not only be developed, but also disseminated and implemented at national and local levels and integrated into clinical practice.

Dissemination involves educating related healthcare providers to improve their awareness, knowledge and understanding of the guideline’s recommendations. It is one part of implementation, which involved translation of evidence-based guidelines into real life practice with improvement of health outcomes for the patients.

Implementation requires an evidence-based strategy involving professional groups and stakeholders and should consider the local cultural and socioeconomic conditions. Cost-effectiveness of implementation programs should be assessed.

Specific steps need to be followed before clinical practice recommendations can be integrated into local clinical practice, particularly in low resource settings.

Steps of implementing wasting diagnosis, treatment, and prevention strategies into the Egyptian health system:

1.     Develop a multidisciplinary working group.

2.     Assess the status of nutritional care delivery, care gaps and current needs.

3.     Select the material to be implemented, agree on the main goals, identify the key recommendations for diagnosis, treatment and prevention and adapt them to the local context or environment.

4.     Identify barriers to, and facilitators of implementation.

5.     Select an implementation framework and its component strategies.

6.     Develop a step-by-step implementation plan:

·       Select the target populations and evaluate the outcome.

·       Identify the local resources to support the implementation.

·       Set timelines.

·       Distribute the tasks to the members.

·       Evaluate the outcomes.

7.     Continuously review the progress and results to determine if the strategy requires modification.

Guideline implementation strategies will focus on the following: -

1.     For Practitioners

·       Educational meetings: conferences, lectures, workshops, grand rounds, seminars, and symposia.

·       Educational materials: printed or electronic information (software).

·       Web-based education: computer-based educational activities.

·       A trained person meets with providers in their practice setting to provide information with the intention of changing the provider’s practice. The information may include feedback on the performance of the provider(s).

·       Reminders: the provision of information verbally, on papers or on a computer screen to prompt a health professional to recall information or to perform or avoid a particular action related to patient care.

·       Optimize professional-patient interactions, through mass media campaigns, reminders, and education materials.

·       Practice tools: tools designed to facilitate behavioral/practice changes, e.g., flow charts.

2.     For Patients and care givers

·       Patient education materials (Arabic booklet): Printed/electronic information aimed at the patient/consumer, family, caregivers, etc.

·       Reminders: the provision of information verbally, on papers or electronically to remind a patient/consumer to perform a particular health-related behaviors.

·       Mass media campaigns.

3.     For Nurses

·       Educational meetings: lectures, workshops or traineeships, seminars, and symposia.

·       Educational materials: printed.

·       A trained person meets with nurses in their practice setting to provide information with the intention of changing the provider’s practice.

·       Reminders: the provision of information verbally, on paper or on a computer screen to prompt them to recall information or to perform or avoid a particular action related to patient care.

·       Practice tools: tools designed to facilitate behavioral/practice changes.

4.     For Stakeholders

Plans have been made to contact with all the health sectors in Egypt including all sectors of the Ministry of Health and Population, National Nutrition Institute, University Hospitals, Ministry of Interior, Ministry of Defense, Non-Governmental Organizations, Private sector, andall Health Care Facilities.

·       Information and communication technology: Electronic decision support, order sets, care maps, electronic health records, office-based personal digital assistants, etc.

·       Any summary of clinical provision of health care over a specified period may include recommendations for clinical action. The information is obtained from medical records, databases, or observations by patients. Summary may be targeted at the individual practitioner or the organization.

·       Administrative policies and procedures.

·       Formularies: Drug safety programs, electronic medication administration records.

5.     Other activities to assist the implementation of the adapted guideline’s recommendations include:

·       International initiative: Dissemination of the presented adapted CPG internationally via sending the final adapted CPG to the Guidelines International Network (GIN) Adaptation Working Group and contacting the CPG developers.

·       Gantt chart has been designedto manage the dissemination and implementation stages for the adapted CPG over an accurate time frame (Appendix).

Evidence to Decision Tables:       

QUESTION B3

Should Transition from F70 to ready-to-use Therapeutic food over 2-3 days vs. change abruptly be used for infants and children

with severe wasting or edema?

POPULATION:

infants and children with severe wasting or edema

INTERVENTION:

Transition from F70 to ready-to-use Therapeutic food over 2-3 days

COMPARISON:

change abruptly

MAIN

OUTCOMES:

 

SETTING:

Inpatient settings during rehabilitation phase

PERSPECTIVE:

 

BACKGROUND:

 

CONFLICT OF INTERESTS:

 

SUMMARY OF JUDGEMENTS

 

 

 

JUDGEMENT

 

 

 

PROBLEM

No

Probably no

Probably yes

Yes

 

Varies

Don't know

DESIRABLE EFFECTS

Trivial

Small

Moderate

Large

 

Varies

Don't know

UNDESIRABLE EFFECTS

Trivial

Small

Moderate

Large

 

Varies

Don't know

CERTAINTY OF

EVIDENCE

Very low

Low

Moderate

High

 

 

No included studies

VALUES

Important uncertainty or variability

Possibly important uncertainty or variability

Probably no important uncertainty or variability

No important uncertainty or variability

 

 

 

BALANCE OF EFFECTS

Favors the comparison

Probably favors the comparison

Does not favor either the intervention or the comparison

Probably favors the intervention

Favors the intervention

Varies

Don't know

RESOURCES REQUIRED

Large costs

Moderate costs

Negligible costs and savings

Moderate savings

Large savings

Varies

Don't know

CERTAINTY OF

EVIDENCE OF

REQUIRED RESOURCES

Very low

Low

Moderate

High

 

 

No included studies

COST EFFECTIVENESS

Favors the comparison

Probably favors the comparison

Does not favor either the intervention or the comparison

Probably favors the intervention

Favors the intervention

Varies

No included studies

EQUITY

Reduced

Probably reduced

Probably no impact

Probably increased

Increased

Varies

Don't know

ACCEPTABILITY

No

Probably no

Probably yes

Yes

Varies

Don't know

FEASIBILITY

No

Probably no

Probably yes

Yes

Varies

Don't know

TYPE OF RECOMMENDATION

Strong recommendation against the

intervention

Conditional recommendation against

the intervention

Conditional recommendation for either the intervention or the

comparison

Conditional recommendation for the

intervention

Strong recommendation for the

intervention

 

QUESTION B4

Should F-100 changed to ready-to-use diet vs. continue on F-100 be used for Children who have been admitted with

complicated severe acute malnutrition and are achieving rapid weight gain on F-100 ?

POPULATION:

Children who have been admitted with complicated severe acute malnutrition and are achieving rapid weight gain on F-100

INTERVENTION:

F-100 changed to ready-to-use diet

COMPARISON:

continue on F-100

MAIN

OUTCOMES:

 

SETTING:

Before discharge to outpatient care

PERSPECTIVE:

 

BACKGROUND:

 

CONFLICT OF INTERESTS:

 

SUMMARY OF JUDGEMENTS

 

 

 

JUDGEMENT

 

 

 

PROBLEM

No

Probably no

Probably yes

Yes

 

Varies

Don't know

DESIRABLE EFFECTS

Trivial

Small

Moderate

Large

 

Varies

Don't know

UNDESIRABLE EFFECTS

Trivial

Small

Moderate

Large

 

Varies

Don't know

CERTAINTY OF

EVIDENCE

Very low

Low

Moderate

High

 

 

No included studies

VALUES

Important uncertainty or variability

Possibly important uncertainty or variability

Probably no important uncertainty or variability

No important uncertainty or variability

 

 

 

BALANCE OF EFFECTS

Favors the comparison

Probably favors the comparison

Does not favor either the intervention or the comparison

Probably favors the intervention

Favors the intervention

Varies

Don't know

RESOURCES REQUIRED

Large costs

Moderate costs

Negligible costs and savings

Moderate savings

Large savings

Varies

Don't know

CERTAINTY OF

EVIDENCE OF

REQUIRED RESOURCES

Very low

Low

Moderate

High

 

 

No included studies

COST EFFECTIVENESS

Favors the comparison

Probably favors the comparison

Does not favor either the intervention or the comparison

Probably favors the intervention

Favors the intervention

Varies

No included studies

EQUITY

Reduced

Probably reduced

Probably no impact

Probably increased

Increased

Varies

Don't know

ACCEPTABILITY

No

Probably no

Probably yes

Yes

 

Varies

Don't know

FEASIBILITY

No

Probably no

Probably yes

Yes

 

Varies

Don't know

TYPE OF RECOMMENDATION

Strong recommendation against the

intervention

Conditional recommendation against

the intervention

Conditional recommendation for either the intervention or the

comparison

Conditional recommendation for the

intervention

Strong recommendation for the

intervention