There is a need to conduct randomized controlled trials (RCTs) to further assess several problems of involvement of the anterior commissure.

There is a need to conduct randomized controlled trials (RCTs) to further assess what is the appropriate treatment of the regional cervical nodes for patients with laryngeal cancer who are treated with an organ-preservation approach?

There is a need to conduct randomized controlled trials (RCTs) to further assess the role of elective neck dissection in patients with radio-recurrent and radio-residual laryngeal cancer?