- The adrenal cortex of the female secretes a large amount of androgens due to lesions occurring in the adrenal cortex (tumor or hyperplasia) or the hypothalamus.
- In adrenal hyperplasia, cortisol precursors accumulate and are shunted into the production of androgens.
- Excessive sexual desire toward the masculine direction (virilization).
- The clinical symptoms correlate to:
-- The age of the animal
-- The stage of lactation.
- Heifers show enlargement of the clitoris and under development of the sexual organs.
- Old cows become fattened with cessation of sexual desire.
- The ovaries are often small or even enlarged.
- The uterus is under developed in heifers and is normal in cows.
- The treatment in such case is not useful.