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Acute Rhinosinusitis

- Methods

➡️Methods of development

➡️Stakeholder Involvement: Individuals who were involved in the development process. Included the above-mentioned Chief Manager, Executive Manager, Assembly Board, Grading Board and Reviewing Board. 

Information about target population experiences were not applicable for this topic.

The adaptation cycle passed over: set-up phase, adaptation phase (Search and screen, assessment: currency, content, quality & /decision/selection) and finalization phase that included revision and external reviewing.

➡️Search method

Electronic database searched:

PubMed, Medline, Egyptian Knowledge Bank, Web of science, Scopus

➡️Keywords:

Acute sinusitis, Acute Rhinosinusitis, Guidelines

➡️Time period searched: from January 2010 to December 2022.

➡️Results

Five national otorhinolaryngologists reviewed the guidelines available. Guidelines from the American Academy of Otolaryngology--Head and Neck Surgery gained the highest scores as regards currency, contents and quality in comparison to other searched guidelines 5-13.

It was graded GRADE by twenty-two experts and reviewed by 6 expert reviewers from different related specialties ORL, Family Medicine and pediatrics. The external review was done through a rating scale as well as open-ended questions.

➡️Setting: Primary, secondary and tertiary care centers & hospitals, and related specialties.

Interpretation of strong and conditional recommendations for an intervention

Audience

Strong recommendation

Conditional recommendation

Patients

Most individuals in this situation would want the recommended course of action; only a small proportion would not.

Formal decision aides are not likely to be needed to help individuals make decisions consistent with their values and preferences.

Most individuals in this situation would want the suggested course of action, but many would not

Clinicians

Most individuals should receive the intervention.

Adherence to the recommendation could be used as a quality criterion or performance indicator.

Different choices will be appropriate for individual patients, who will require assistance in arriving at a management decision consistent with his or her values and preferences. Decision aides may be useful in helping individuals make decisions consistent with their values and preferences.

Policymakers

The recommendation can be adopted as policy in most situations.

Policy-making will require substantial debate and involvement of various stakeholders.

WHO handbook for guideline development – 2nd ed.

Chapter 10, page 129

The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to Decision frameworks (GRADE Working Group 2013)

Grade

Definition

High

 

We are very confident that the true effect lies close to that of the estimate of the effect.

Moderate

 

We are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different

Low

 

Our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.

Very Low

 

We have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect